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Página de Inicio arrow Artículos Científicos arrow Anti-Immunoglobulin E in the Treatment of Refractory Atopic Dermatitis
Anti-Immunoglobulin E in the Treatment of Refractory Atopic Dermatitis Imprimir E-Mail
Southern Medical Journal:
June 2010 - Volume 103 - Issue 6 - pp 554-558

Case Reports
Anti-Immunoglobulin E in the Treatment of Refractory Atopic Dermatitis
Amrol, David MD
Abstract
Atopic dermatitis (AD) is a common diagnosis seen in both children and
adults, and it is often the first manifestation of atopic disease.
Research has shown a strong correlation between serum IgE levels, the
severity of atopic dermatitis, and co-existing asthma and/or allergic
rhinitis.18 Omalizumab (Xolair®, East Hanover, NJ; Genentech, South
San Francisco, CA) is a monoclonal antibody to human IgE and is
currently Food and Drug Administration (FDA) approved for the
treatment of asthma. We present 3 patients with severe, treatment
resistant atopic dermatitis whose cutaneous symptoms significantly
improved by treatment with omalizumab.
 
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