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Página de Inicio arrow Noticias arrow Scleroderma Research
Scleroderma Research Imprimir E-Mail

In a bold attempt to control scleroderma, physicians at Duke University Medical Center are leading a national study to test whether stem cell transplants can reconstruct defective immune systems.


At this time, the predominant therapy for this disease is cyclophosphamide; however, about 50% of patients with severe organ involvement die within 5 years of diagnosis.

This study (Scleroderma Cyclophosphamide or Transplantation - SCOT) will increase the dose and duration of cyclophosphamide and compare this regimen against stem cell transplants, using purified cells derived from a patient's own blood.

This 7-year randomized clinical trial will enroll 226 patients at 36 institutions throughout the US. If successful, the therapy would represent the first therapy ever to treat and potentially reverse the disease itself, not just alleviate its symptoms.

 
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